Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
gptkb:SHIP1
|
| gptkbp:associatedWith |
leukemia
autoimmune diseases |
| gptkbp:domain |
SH2 domain
phosphatase domain |
| gptkbp:encodes |
gptkb:SHIP1_protein
|
| gptkbp:Entrez_Gene_ID |
3635
ENSG00000168918 |
| gptkbp:expressedIn |
hematopoietic cells
|
| gptkbp:fullName |
gptkb:inositol_polyphosphate-5-phosphatase_D
|
| gptkbp:function |
negative regulation of immune cell signaling
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity |
| https://www.w3.org/2000/01/rdf-schema#label |
INPP5D
|
| gptkbp:locatedOnChromosome |
2q37.1
|
| gptkbp:mutationAssociatedWith |
immunodeficiency
|
| gptkbp:OMIM |
600871
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Inpp5d
|
| gptkbp:regulates |
PI3K signaling pathway
|
| gptkbp:UniProtID |
Q92835
|
| gptkbp:bfsParent |
gptkb:Alzheimer's_disease_pathway
gptkb:SHIP1 |
| gptkbp:bfsLayer |
7
|