Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
Src homology 2 domain-containing inositol 5-phosphatase 1
INPP5D protein |
| gptkbp:domain |
SH2 domain
phosphatase domain |
| gptkbp:encodedBy |
INPP5D gene
|
| gptkbp:expressedIn |
hematopoietic cells
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
|
| https://www.w3.org/2000/01/rdf-schema#label |
SHIP1 protein
|
| gptkbp:involvedIn |
immune cell signaling
|
| gptkbp:locale |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:modulatedBy |
B cell receptor signaling
T cell receptor signaling Fc receptor signaling |
| gptkbp:molecularWeight |
145 kDa
|
| gptkbp:mutationAssociatedWith |
immunodeficiency
autoimmune disease |
| gptkbp:orthologIn |
gptkb:Mus_musculus
|
| gptkbp:regulates |
apoptosis
cell differentiation cell proliferation PI3K signaling pathway |
| gptkbp:UniProtID |
Q92835
|
| gptkbp:bfsParent |
gptkb:INPP5D
|
| gptkbp:bfsLayer |
8
|