Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:discoveredBy |
Barres et al.
|
| gptkbp:encodedBy |
CNTF gene
|
| gptkbp:expressedIn |
central nervous system
peripheral nervous system glial cells |
| gptkbp:foundIn |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:fullName |
Ciliary neurotrophic factor
|
| gptkbp:function |
gptkb:growth_factor
supports survival of neurons promotes differentiation of neural cells |
| gptkbp:gene |
gptkb:CNTF
|
| gptkbp:HGNC_ID |
2180
|
| gptkbp:locatedOnChromosome |
11q12.1
|
| gptkbp:molecularWeight |
22.8 kDa
|
| gptkbp:OMIM |
162350
|
| gptkbp:recipient |
CNTFR
|
| gptkbp:relatedTo |
motor neuron survival
astrocyte differentiation |
| gptkbp:sequence |
200 amino acids
|
| gptkbp:structure |
gptkb:cytokine_family
|
| gptkbp:UniProtID |
P26441
|
| gptkbp:usedIn |
neurodegenerative disease research
ALS clinical trials |
| gptkbp:bfsParent |
gptkb:LIFR
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
CNTF
|