Statements (66)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Cell
|
| gptkbp:associated_with |
autoimmune diseases
|
| gptkbp:code |
gptkb:IL17_A_gene
|
| gptkbp:enhances |
expression of adhesion molecules
production of other cytokines |
| gptkbp:has_role |
host defense against pathogens
|
| https://www.w3.org/2000/01/rdf-schema#label |
IL-17 A
|
| gptkbp:increased |
neutrophil recruitment
|
| gptkbp:influences |
bone metabolism
|
| gptkbp:initiated_by |
NF-k B pathway
apoptosis of certain cells |
| gptkbp:investigates |
gptkb:Crohn's_disease
gptkb:ulcerative_colitis gptkb:rheumatoid_arthritis gptkb:multiple_sclerosis psoriasis |
| gptkbp:involved_in |
inflammatory responses
chronic inflammation |
| gptkbp:is_associated_with |
increased risk of infections
|
| gptkbp:is_involved_in |
gptkb:idiopathic_pulmonary_fibrosis
gptkb:disease gptkb:diabetes gptkb:asthma gptkb:systemic_lupus_erythematosus gptkb:neurodegenerative_diseases eye diseases immune response liver diseases chronic pain metabolic syndrome obesity neuroinflammation fibrosis cardiovascular diseases fungal infections chronic kidney disease skin diseases cancer progression atherosclerosis viral infections bacterial infections atopic dermatitis allergic rhinitis gastrointestinal diseases chronic obstructive pulmonary disease tissue remodeling hematological disorders endocrine disorders oral diseases immunological disorders parasitic infections musculoskeletal diseases Th17 cell differentiation |
| gptkbp:is_part_of |
gptkb:IL-17_family
|
| gptkbp:is_regulated_by |
transcription factors
|
| gptkbp:is_targeted_at |
biologic therapies
|
| gptkbp:knockouts |
gptkb:IL-17_receptor
|
| gptkbp:measures |
serum levels
|
| gptkbp:participated_in |
IL-6 production
|
| gptkbp:produced_by |
gptkb:T-helper_17_cells
|
| gptkbp:promotes |
angiogenesis
|
| gptkbp:regulates |
gptkb:matrix_metalloproteinases
|
| gptkbp:security |
activated T cells
|
| gptkbp:weight |
approximately 15 k Da
|
| gptkbp:bfsParent |
gptkb:Taltz
|
| gptkbp:bfsLayer |
5
|