|
gptkbp:instance_of
|
gptkb:pharmaceuticals
|
|
gptkbp:approves
|
gptkb:FDA
|
|
gptkbp:class
|
gptkb:monoclonal_antibody
|
|
gptkbp:clinical_trial
|
ongoing
completed
Phase 3
active ankylosing spondylitis
active psoriatic arthritis
chronic plaque psoriasis
|
|
gptkbp:contraindication
|
hypersensitivity to ixekizumab
|
|
gptkbp:dosage_form
|
pre-filled syringe
|
|
gptkbp:drug_interactions
|
immunosuppressants
live vaccines
|
|
gptkbp:duration
|
long-term therapy
|
|
gptkbp:effective_date
|
2016-03-24
|
|
gptkbp:financial_support
|
available
|
|
gptkbp:formulation
|
solution for injection
|
|
gptkbp:frequency
|
once every 4 weeks after initial doses
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Taltz
|
|
gptkbp:ingredients
|
gptkb:ixekizumab
|
|
gptkbp:invention
|
patented
|
|
gptkbp:is_monitored_by
|
signs of infection
|
|
gptkbp:manufacturer
|
gptkb:Eli_Lilly_and_Company
|
|
gptkbp:marketed_as
|
gptkb:Australia
gptkb:Canada
gptkb:European_Union
gptkb:United_States
|
|
gptkbp:mechanism_of_action
|
IL-17 A inhibition
|
|
gptkbp:patient_population
|
adults
|
|
gptkbp:pharmacokinetics
|
subcutaneous absorption
IL-17 A blockade
|
|
gptkbp:previous_name
|
no
|
|
gptkbp:price
|
high
|
|
gptkbp:provides_guidance_on
|
recommended for moderate to severe cases
|
|
gptkbp:requires
|
provided by manufacturer
|
|
gptkbp:research
|
ongoing
|
|
gptkbp:research_focus
|
efficacy in different populations
long-term safety
comparative effectiveness
|
|
gptkbp:route_of_administration
|
subcutaneous injection
|
|
gptkbp:safety_measures
|
risk of serious infections
|
|
gptkbp:side_effect
|
fatigue
headache
nausea
allergic reactions
neurological disorders
injection site reactions
gastrointestinal disorders
upper respiratory infections
serious infections
|
|
gptkbp:storage
|
refrigerated
|
|
gptkbp:targets
|
gptkb:IL-17_A
|
|
gptkbp:type_of_care
|
important for efficacy
|
|
gptkbp:type_of_insurance
|
varies by plan
|
|
gptkbp:used_for
|
gptkb:ankylosing_spondylitis
gptkb:psoriatic_arthritis
psoriasis
|
|
gptkbp:bfsParent
|
gptkb:Eli_Lilly
|
|
gptkbp:bfsLayer
|
4
|