idiopathic pulmonary fibrosis
GPTKB entity
Statements (60)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Oncology
|
| gptkbp:affects |
lungs
|
| gptkbp:clinical_trial |
gptkb:Nintedanib
gptkb:Pirfenidone fatigue weight loss muscle weakness clubbing of fingers crackling sounds in lungs |
| gptkbp:complication |
respiratory failure
pulmonary hypertension |
| gptkbp:condition |
gastroesophageal reflux disease
connective tissue disease |
| gptkbp:death |
high
varies by individual |
| gptkbp:diagnosis |
variable
heart failure high-resolution CT scan histopathological findings chronic obstructive pulmonary disease pulmonary embolism clinical history radiological findings other interstitial lung diseases lung biopsy |
| gptkbp:environmental_risk_factors |
asbestos exposure
silica exposure wood dust exposure |
| gptkbp:genetic_predisposition |
familial cases
SFTPC mutations MUC5 B polymorphism |
| https://www.w3.org/2000/01/rdf-schema#label |
idiopathic pulmonary fibrosis
|
| gptkbp:pathway |
inflammation
fibrosis lung scarring |
| gptkbp:patient_population |
more common in men
more common in older adults |
| gptkbp:premiered_on |
progressive
gradual |
| gptkbp:prevalence |
approximately 3 million cases worldwide
|
| gptkbp:public_awareness |
gptkb:World_IPF_Day
gptkb:educational_resources patient advocacy groups |
| gptkbp:research_focus |
biomarkers
genetic factors environmental exposures |
| gptkbp:risk_factor |
age
smoking |
| gptkbp:symptoms |
shortness of breath
chronic cough |
| gptkbp:treatment |
pulmonary rehabilitation
oxygen therapy antifibrotic medications |
| gptkbp:type_of_care |
palliative care
nutritional support psychosocial support |
| gptkbp:bfsParent |
gptkb:ALK
gptkb:Incyte_Biosciences gptkb:IL-17_A |
| gptkbp:bfsLayer |
6
|