|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
CDw217
IL-17 receptor A
IL-17R
|
|
gptkbp:associatedWith
|
asthma
autoimmune diseases
inflammatory diseases
psoriasis
immune response
rheumatoid arthritis
|
|
gptkbp:discoveredBy
|
1995
|
|
gptkbp:domain
|
fibronectin type III domain
SEFIR domain
|
|
gptkbp:encodedBy
|
IL17RA gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000177663
|
|
gptkbp:expressedIn
|
endothelial cells
fibroblasts
epithelial cells
hematopoietic tissues
|
|
gptkbp:externalLink
|
https://www.uniprot.org/uniprot/Q96F46
|
|
gptkbp:family
|
interleukin-17 receptor family
|
|
gptkbp:fullName
|
Interleukin-17 receptor A
|
|
gptkbp:function
|
receptor for interleukin-17A
receptor for interleukin-17F
|
|
gptkbp:gene
|
IL17RA
|
|
gptkbp:HGNC_ID
|
HGNC:5987
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IL-17RA
|
|
gptkbp:interactsWith
|
gptkb:IL-17A
IL-17F
ACT1 (TRAF3IP2)
|
|
gptkbp:locatedOnChromosome
|
chromosome 22q11.1
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
~96 kDa
|
|
gptkbp:OMIM
|
604378
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Danio_rerio
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
3JVF
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:RefSeq
|
NM_014339
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:structure
|
single-pass type I membrane protein
|
|
gptkbp:target
|
therapeutic antibodies
|
|
gptkbp:type
|
gptkb:MAPK_pathway
gptkb:NF-κB_pathway
|
|
gptkbp:UniProtID
|
Q96F46
|
|
gptkbp:bfsParent
|
gptkb:interleukin-17A
|
|
gptkbp:bfsLayer
|
6
|