IL-17A

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf cytokine
gptkbp:alsoKnownAs Interleukin-17A
gptkbp:discoveredIn 1993
gptkbp:encodedBy gptkb:IL17A_gene
gptkbp:function pro-inflammatory cytokine
recruits neutrophils
stimulates production of other cytokines
gptkbp:HGNC_ID 5981
https://www.w3.org/2000/01/rdf-schema#label IL-17A
gptkbp:involvedIn asthma
multiple sclerosis
autoimmune diseases
psoriasis
rheumatoid arthritis
host defense against bacteria
host defense against fungi
gptkbp:locatedOnChromosome gptkb:6p12
gptkbp:memberOf IL-17 family
gptkbp:molecularWeight 35 kDa
gptkbp:producedBy gptkb:gamma-delta_T_cells
gptkb:Th17_cells
gptkb:innate_lymphoid_cells
natural killer T cells
gptkbp:recipient gptkb:IL-17RA
gptkb:IL-17RC
gptkbp:structure gptkb:protein
homodimer
gptkbp:target gptkb:secukinumab
gptkb:ixekizumab
brodalumab
gptkbp:UniProtID gptkb:Q16552
gptkbp:bfsParent gptkb:interleukin-17A
gptkbp:bfsLayer 6