IL-15Rα

GPTKB entity

Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:protein
cell surface receptor
gptkbp:alternativeSplicing yes
gptkbp:associatedWith gptkb:cancer
autoimmune diseases
inflammatory diseases
gptkbp:binds Interleukin-15
gptkbp:component IL-15 receptor complex
gptkbp:discoveredBy 1995
gptkbp:encodedBy IL15RA gene
gptkbp:expressedIn gptkb:NK_cells
gptkb:T_cells
dendritic cells
immune cells
monocytes
gptkbp:formsComplexWith gptkb:common_gamma_chain_(γc)
IL-2Rβ
gptkbp:fullName Interleukin-15 receptor alpha subunit
gptkbp:function regulates immune response
mediates IL-15 signaling
gptkbp:gene IL15RA
https://www.w3.org/2000/01/rdf-schema#label IL-15Rα
gptkbp:locatedOnChromosome 10p15
gptkbp:location gptkb:endosome
gptkb:cell_membrane
gptkbp:molecularWeight ~30 kDa
gptkbp:orthologInMouse Il15ra
gptkbp:PDB 4GS7
gptkbp:postTranslationalModification phosphorylation
glycosylation
gptkbp:UniProtID Q13261
gptkbp:bfsParent gptkb:IL-15
gptkb:interleukin-15
gptkbp:bfsLayer 8