Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:signaling_molecule
|
| gptkbp:activatedBy |
gptkb:JAK1
gptkb:STAT6 gptkb:TYK2 |
| gptkbp:associatedWith |
asthma
fibrosis allergic diseases |
| gptkbp:cause |
gene expression changes
|
| gptkbp:inhibitedBy |
gptkb:lebrikizumab
gptkb:tralokinumab gptkb:dupilumab |
| gptkbp:involves |
gptkb:interleukin-13
|
| gptkbp:occurredIn |
gptkb:T_helper_2_cells
macrophages epithelial cells |
| gptkbp:recipient |
gptkb:IL-13Rα1
gptkb:IL-4Rα |
| gptkbp:regulates |
gptkb:immune_response
inflammation |
| gptkbp:result |
mucus production
airway hyperresponsiveness IgE production |
| gptkbp:bfsParent |
gptkb:dupilumab
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
IL-13 signaling
|