Statements (25)
Predicate | Object |
---|---|
gptkbp:instanceOf |
signaling molecule
|
gptkbp:activatedBy |
gptkb:JAK1
gptkb:STAT6 gptkb:TYK2 |
gptkbp:associatedWith |
asthma
fibrosis allergic diseases |
gptkbp:cause |
gene expression changes
|
https://www.w3.org/2000/01/rdf-schema#label |
IL-13 signaling
|
gptkbp:inhibitedBy |
gptkb:lebrikizumab
gptkb:tralokinumab gptkb:dupilumab |
gptkbp:involves |
gptkb:interleukin-13
|
gptkbp:occurredIn |
gptkb:T_helper_2_cells
macrophages epithelial cells |
gptkbp:recipient |
gptkb:IL-13Rα1
gptkb:IL-4Rα |
gptkbp:regulates |
inflammation
immune response |
gptkbp:result |
mucus production
airway hyperresponsiveness IgE production |
gptkbp:bfsParent |
gptkb:dupilumab
|
gptkbp:bfsLayer |
7
|