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gptkbp:instanceOf
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gptkb:protein
|
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gptkbp:alternativeName
|
PP12
Placental protein 12
|
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gptkbp:category
|
insulin-like growth factor binding protein family
|
|
gptkbp:encodedBy
|
IGFBP1 gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000146678
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gptkbp:expressedIn
|
gptkb:kidney
liver
decidua
|
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gptkbp:foundIn
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gptkb:plasma
|
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gptkbp:fullName
|
Insulin-like growth factor-binding protein 1
|
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gptkbp:function
|
binds insulin-like growth factors
|
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gptkbp:gene
|
IGFBP1
|
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gptkbp:HGNC_ID
|
HGNC:5465
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IGFBP-1
|
|
gptkbp:interactsWith
|
gptkb:insulin-like_growth_factor_II
insulin-like growth factor I
|
|
gptkbp:locatedOnChromosome
|
7p12-p13
|
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gptkbp:modulatedBy
|
IGF bioavailability
|
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gptkbp:molecularWeight
|
28-32 kDa
|
|
gptkbp:OMIM
|
146730
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
1B9G
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:RefSeq
|
NM_000596
|
|
gptkbp:regulates
|
gptkb:IGF-II
gptkb:IGF-I
regulated by insulin
regulated by glucocorticoids
regulated by fasting
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gptkbp:significance
|
marker for insulin sensitivity
marker for metabolic disorders
|
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gptkbp:structure
|
contains IGFBP domain
|
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gptkbp:UniProtID
|
P08833
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gptkbp:bfsParent
|
gptkb:FOXO
|
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gptkbp:bfsLayer
|
7
|