Heat shock protein beta-1

URI: https://gptkb.org/entity/Heat_shock_protein_beta-1

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	gptkb:HSP27 gptkb:HSPB1
gptkbp:associatedWith	gptkb:Charcot-Marie-Tooth_disease distal hereditary motor neuropathy
gptkbp:encodedBy	gptkb:HSPB1_gene
gptkbp:Entrez_Gene_ID	3315
gptkbp:expressedIn	various tissues
gptkbp:function	molecular chaperone prevents aggregation of denatured proteins involved in stress resistance regulates actin cytoskeleton dynamics
https://www.w3.org/2000/01/rdf-schema#label	Heat shock protein beta-1
gptkbp:inducedBy	oxidative stress heat shock cellular stress
gptkbp:interactsWith	gptkb:actin tubulin other heat shock proteins
gptkbp:locatedOnChromosome	7q11.23
gptkbp:location	gptkb:nucleus gptkb:cytoplasm
gptkbp:memberOf	small heat shock protein family
gptkbp:molecularWeight	27 kDa
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:PDB	4MJH
gptkbp:postTranslationalModification	phosphorylation
gptkbp:RefSeq	NP_001531.1
gptkbp:significance	biomarker for cancer involved in neurodegenerative diseases
gptkbp:structure	forms homodimers and oligomers
gptkbp:UniProtID	gptkb:P04792
gptkbp:bfsParent	gptkb:HSP27
gptkbp:bfsLayer	7