|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:H3R
histamine receptor H3
|
|
gptkbp:associatedWith
|
gptkb:attention_deficit_hyperactivity_disorder
cognition
schizophrenia
obesity
narcolepsy
allergic responses
sleep-wake regulation
|
|
gptkbp:discoveredBy
|
1999
|
|
gptkbp:encodes
|
gptkb:histamine_H3_receptor
|
|
gptkbp:Entrez_Gene_ID
|
11255
ENSG00000132437
|
|
gptkbp:expressedIn
|
brain
central nervous system
peripheral nervous system
|
|
gptkbp:function
|
gptkb:G_protein-coupled_receptor
modulates neurotransmitter release
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
5171
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HRH3
|
|
gptkbp:length
|
445 amino acids
|
|
gptkbp:locatedOnChromosome
|
20q13.33
|
|
gptkbp:modulatedBy
|
postsynaptic signaling
presynaptic neurotransmitter release
|
|
gptkbp:molecularWeight
|
48 kDa
|
|
gptkbp:OMIM
|
604867
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Hrh3
|
|
gptkbp:product
|
gptkb:Histamine_H3_receptor
|
|
gptkbp:proteinFamily
|
gptkb:G_protein-coupled_receptor
histamine receptor family
|
|
gptkbp:RefSeq
|
NM_007233
|
|
gptkbp:RefSeq_Protein
|
NP_009164
|
|
gptkbp:regulates
|
dopamine release
histamine release
GABA release
acetylcholine release
glutamate release
norepinephrine release
serotonin release
|
|
gptkbp:symbol
|
gptkb:HRH3
|
|
gptkbp:target
|
antihistamines
agonists
inverse agonists
|
|
gptkbp:UniProtID
|
Q9Y5N1
|
|
gptkbp:bfsParent
|
gptkb:H3_receptor
gptkb:histamine_H3_receptor
|
|
gptkbp:bfsLayer
|
7
|