Statements (37)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:G_protein-coupled_receptor
|
| gptkbp:alternativeName |
gptkb:H3R
gptkb:HRH3 |
| gptkbp:binds |
gptkb:histamine
|
| gptkbp:coupledTo |
gptkb:Gi/o_proteins
|
| gptkbp:discoveredIn |
1983
|
| gptkbp:encodedBy |
gptkb:HRH3_gene
|
| gptkbp:enemyOf |
gptkb:ciproxifan
gptkb:immepip gptkb:pitolisant imetit |
| gptkbp:foundIn |
brain
peripheral nervous system |
| gptkbp:function |
modulates neurotransmitter release
|
| https://www.w3.org/2000/01/rdf-schema#label |
histamine H3 receptor
|
| gptkbp:locatedIn |
central nervous system
|
| gptkbp:locatedOnChromosome |
20q13.33
|
| gptkbp:regulates |
dopamine release
GABA release acetylcholine release glutamate release norepinephrine release serotonin release histamine synthesis |
| gptkbp:species |
gptkb:human
gptkb:mouse right |
| gptkbp:targetOfDrug |
schizophrenia
obesity ADHD narcolepsy cognitive disorders |
| gptkbp:type |
inhibits adenylate cyclase
decreases cAMP levels |
| gptkbp:UniProtID |
Q9Y5N1
|
| gptkbp:bfsParent |
gptkb:antihistamine
|
| gptkbp:bfsLayer |
6
|