|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
MHC class II, DR alpha
HLA class II histocompatibility antigen, DR alpha chain
|
|
gptkbp:associatedWith
|
type 1 diabetes
autoimmune diseases
rheumatoid arthritis
|
|
gptkbp:discoveredBy
|
histocompatibility studies
|
|
gptkbp:disulfideBond
|
present
|
|
gptkbp:encodes
|
HLA class II histocompatibility antigen, DR alpha chain
|
|
gptkbp:Entrez_Gene_ID
|
3122
|
|
gptkbp:expressedIn
|
antigen-presenting cells
|
|
gptkbp:formsComplexWith
|
gptkb:HLA-DRB1
|
|
gptkbp:formsHeterodimerWith
|
gptkb:HLA-DRB1
|
|
gptkbp:foundIn
|
gptkb:cell_membrane
|
|
gptkbp:function
|
antigen presentation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:glycosylation
|
present
|
|
gptkbp:has3PrimeUTR
|
present
|
|
gptkbp:has5PrimeUTR
|
present
|
|
gptkbp:hasAllele
|
HLA-DRA*01:01
HLA-DRA*01:02
|
|
gptkbp:hasPromoter
|
present
|
|
gptkbp:hasProteinLength
|
254 amino acids
|
|
gptkbp:hasPseudogene
|
HLA-DRAX
|
|
gptkbp:hasTranscriptVariant
|
NM_002124
NM_019111
|
|
gptkbp:HGNC_ID
|
4948
|
|
gptkbp:involvedIn
|
gptkb:immune_response
|
|
gptkbp:isHighlyConserved
|
yes
|
|
gptkbp:locatedOnChromosome
|
gptkb:6p21.3
gptkb:chromosome_6
|
|
gptkbp:molecularWeight
|
29 kDa
|
|
gptkbp:numberOfExons
|
5
|
|
gptkbp:OMIM
|
142860
|
|
gptkbp:orthologInMouse
|
H2-Aa
|
|
gptkbp:partOf
|
gptkb:major_histocompatibility_complex
gptkb:HLA-DR
|
|
gptkbp:product
|
HLA-DRA protein
|
|
gptkbp:proteinFamily
|
immunoglobulin-like domain
HLA class II alpha chain paralogs
|
|
gptkbp:referenceGenome
|
NC_000006.12
|
|
gptkbp:regulates
|
gptkb:CIITA
gptkb:CREB1
RFX5
|
|
gptkbp:signalPeptide
|
present
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:transmembraneDomains
|
present
|
|
gptkbp:UniProtID
|
P01903
|
|
gptkbp:bfsParent
|
gptkb:DR1A
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HLA-DRA
|