Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:affiliatedWith |
gptkb:major_histocompatibility_complex_(MHC)
|
gptkbp:associatedWith |
gptkb:psoriatic_arthritis
inflammatory bowel disease reactive arthritis ankylosing spondylitis |
gptkbp:binds |
gptkb:beta-2_microglobulin
|
gptkbp:discoveredIn |
1973
|
gptkbp:encodedBy |
gptkb:HLA-B_gene
|
gptkbp:expressedIn |
cell surface
|
gptkbp:foundIn |
humans
|
gptkbp:function |
presentation of peptide antigens to immune system
|
gptkbp:hasAllele |
HLA-B*27:02
HLA-B*27:04 HLA-B*27:05 HLA-B*27:07 |
gptkbp:hasPolymorphism |
true
|
gptkbp:hasRole |
immune response
|
https://www.w3.org/2000/01/rdf-schema#label |
HLA-B27 protein
|
gptkbp:locatedOnChromosome |
gptkb:chromosome_6
|
gptkbp:memberOf |
gptkb:HLA_class_I_molecules
|
gptkbp:molecularWeight |
~45 kDa
|
gptkbp:presentsAntigenTo |
cell surface receptor
|
gptkbp:recognizedBy |
gptkb:cytotoxic_T_cells
|
gptkbp:structureType |
heterodimer
|
gptkbp:usedIn |
diagnosis of spondyloarthropathies
|
gptkbp:bfsParent |
gptkb:B27
|
gptkbp:bfsLayer |
7
|