Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
immune response
|
| gptkbp:activatedBy |
cytokines
antigen-presenting cells |
| gptkbp:alsoKnownAs |
gptkb:CD8+_T_cells
|
| gptkbp:developedBy |
thymocyte
|
| gptkbp:discoveredBy |
gptkb:Peter_Doherty
gptkb:Rolf_Zinkernagel |
| gptkbp:expressedIn |
gptkb:CD8_glycoprotein
|
| gptkbp:foundIn |
blood
lymphoid tissue |
| gptkbp:function |
kill damaged cells
kill tumor cells kill virus-infected cells |
| https://www.w3.org/2000/01/rdf-schema#label |
cytotoxic T cells
|
| gptkbp:involves |
immunotherapy
autoimmune diseases graft rejection viral clearance |
| gptkbp:marking |
gptkb:T-cell_receptor_(TCR)
gptkb:CD8 |
| gptkbp:mechanismOfAction |
induce apoptosis
release granzymes release perforin |
| gptkbp:produces |
gptkb:interferon-gamma
gptkb:tumor_necrosis_factor-alpha |
| gptkbp:recognizedBy |
antigen presented by MHC class I
|
| gptkbp:role |
adaptive immune response
immunological memory |
| gptkbp:subspecies |
gptkb:effector_T_cell
memory T cell |
| gptkbp:type |
T lymphocyte
|
| gptkbp:bfsParent |
gptkb:CD8
|
| gptkbp:bfsLayer |
6
|