Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
low oxygen levels
|
| gptkbp:binds |
gptkb:hypoxia_response_elements_(HREs)
|
| gptkbp:component |
transcription factors
|
| gptkbp:discoveredBy |
gptkb:Gregg_L._Semenza
|
| gptkbp:fullName |
gptkb:Hypoxia-inducible_factor_family
|
| gptkbp:function |
regulation of cellular response to hypoxia
|
| gptkbp:gene |
gptkb:HIF
|
| https://www.w3.org/2000/01/rdf-schema#label |
HIF family
|
| gptkbp:includes |
gptkb:HIF-1α
gptkb:HIF-2α gptkb:HIF-3α |
| gptkbp:inhibitedBy |
normoxia
|
| gptkbp:regulates |
apoptosis
cell proliferation angiogenesis cellular metabolism erythropoietin gene expression |
| gptkbp:relatedTo |
cancer progression
inflammatory diseases ischemic diseases |
| gptkbp:bfsParent |
gptkb:hypoxia-inducible_factor_1_(HIF-1)
|
| gptkbp:bfsLayer |
6
|