HECT E3 ubiquitin ligase family
GPTKB entity
Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:catalyzes |
transfer of ubiquitin from E2 enzyme to substrate protein
|
| gptkbp:domain |
gptkb:HECT_domain
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
ubiquitin-protein transferase activity
|
| https://www.w3.org/2000/01/rdf-schema#label |
HECT E3 ubiquitin ligase family
|
| gptkbp:involvedIn |
ubiquitination
|
| gptkbp:involves |
gptkb:cancer
neurodegenerative diseases cell signaling protein degradation |
| gptkbp:memberOf |
gptkb:E3_ubiquitin_ligase_superfamily
|
| gptkbp:notableMember |
gptkb:E6AP
gptkb:ITCH gptkb:NEDD4 gptkb:SMURF1 |
| gptkbp:bfsParent |
gptkb:HERC2_gene
|
| gptkbp:bfsLayer |
7
|