|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:ataxia-telangiectasia
|
|
gptkbp:discoveredBy
|
1998
|
|
gptkbp:encodedBy
|
H2AFX gene
|
|
gptkbp:function
|
DNA repair
chromatin remodeling
histone variant
|
|
gptkbp:gene
|
H2AFX
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
H2AX
|
|
gptkbp:interactsWith
|
gptkb:ATM_kinase
gptkb:DNA-PKcs
gptkb:MDC1
gptkb:ATR_kinase
|
|
gptkbp:involves
|
genome stability
cell cycle checkpoint
|
|
gptkbp:length
|
143 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_11q23.2
|
|
gptkbp:molecularWeight
|
15.1 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
H2afx
|
|
gptkbp:orthologInYeast
|
HTA2
|
|
gptkbp:phosphorylated_form
|
γ-H2AX
|
|
gptkbp:phosphorylates
|
serine 139
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:relatedTo
|
gptkb:non-homologous_end_joining
apoptosis
homologous recombination
|
|
gptkbp:role
|
marker of DNA double-strand breaks
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
P16104
|
|
gptkbp:bfsParent
|
gptkb:ATM_kinase
gptkb:DNA-PK_holoenzyme
gptkb:DNA-PKcs
gptkb:DNA-dependent_protein_kinase
gptkb:PRKDC
gptkb:ATR_kinase
|
|
gptkbp:bfsLayer
|
7
|