Guanine nucleotide-binding protein G(s), alpha subunit

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:Guanine_nucleotide-binding_protein_G(s)_subunit_alpha gptkb:G(s)_alpha gptkb:GNAS_complex_locus
gptkbp:component	heterotrimeric G protein complex
gptkbp:encodedBy	gptkb:GNAS_gene
gptkbp:expressedIn	many tissues
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	mediates signal transduction stimulates adenylate cyclase
gptkbp:gene	gptkb:GNAS
https://www.w3.org/2000/01/rdf-schema#label	Guanine nucleotide-binding protein G(s), alpha subunit
gptkbp:interactsWith	gptkb:G_protein_beta-gamma_subunits gptkb:beta-adrenergic_receptor gptkb:adenylate_cyclase
gptkbp:involves	gptkb:cAMP_signaling_pathway
gptkbp:locatedOnChromosome	20q13.32
gptkbp:location	gptkb:plasma_membrane
gptkbp:molecularWeight	~45 kDa
gptkbp:mutationAssociatedWith	gptkb:McCune-Albright_syndrome gptkb:progressive_osseous_heteroplasia gptkb:pseudohypoparathyroidism_type_Ia
gptkbp:OMIM	139320
gptkbp:PDB	gptkb:1AZT
gptkbp:postTranslationalModification	palmitoylation phosphorylation myristoylation
gptkbp:regulates	adenylate cyclase activity cAMP production
gptkbp:subunit	gptkb:G_protein_Gs
gptkbp:UniProtID	P63092
gptkbp:bfsParent	gptkb:GNAS
gptkbp:bfsLayer	7