Guanine nucleotide-binding protein G(s) subunit alpha

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:GNAS_complex_locus Gαs stimulatory G-protein alpha subunit
gptkbp:binds	gptkb:GDP gptkb:GTP
gptkbp:encodedBy	gptkb:GNAS_gene
gptkbp:expressedIn	many tissues
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	G protein alpha subunit activates adenylyl cyclase mediates signal transduction
gptkbp:gene	gptkb:GNAS
https://www.w3.org/2000/01/rdf-schema#label	Guanine nucleotide-binding protein G(s) subunit alpha
gptkbp:interactsWith	gptkb:G_protein-coupled_receptors adenylyl cyclase
gptkbp:involves	gptkb:cAMP_signaling_pathway G protein-coupled receptor signaling pathway
gptkbp:locatedOnChromosome	20q13.32
gptkbp:location	gptkb:plasma_membrane
gptkbp:molecularWeight	~45 kDa
gptkbp:mutationAssociatedWith	gptkb:McCune-Albright_syndrome gptkb:progressive_osseous_heteroplasia gptkb:pseudohypoparathyroidism_type_Ia
gptkbp:OMIM	139320
gptkbp:PDB	gptkb:1AZT
gptkbp:postTranslationalModification	palmitoylation myristoylation
gptkbp:structure	contains GTPase domain
gptkbp:subunit	heterotrimeric G protein complex
gptkbp:UniProtID	P63092
gptkbp:bfsParent	gptkb:Gs_protein
gptkbp:bfsLayer	6