Growth arrest and DNA-damage-inducible protein GADD45 alpha
GPTKB entity
Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:GADD45
gptkb:GADD45A gptkb:GADD45_alpha |
| gptkbp:associatedWith |
gptkb:cancer
cellular senescence inflammatory response |
| gptkbp:encodedBy |
GADD45A gene
|
| gptkbp:Entrez_Gene_ID |
1647
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
DNA repair
apoptosis regulation cell cycle arrest |
| https://www.w3.org/2000/01/rdf-schema#label |
Growth arrest and DNA-damage-inducible protein GADD45 alpha
|
| gptkbp:interactsWith |
gptkb:PCNA
gptkb:CDK1 gptkb:MAP3K4 |
| gptkbp:involvedIn |
cellular response to stress
p53 signaling pathway |
| gptkbp:length |
165 amino acids
|
| gptkbp:locatedOnChromosome |
1p31.2
|
| gptkbp:molecularWeight |
18 kDa
|
| gptkbp:orthologIn |
Gadd45a (mouse)
|
| gptkbp:regulates |
regulated by p53
induced by DNA damage induced by genotoxic stress regulated by BRCA1 |
| gptkbp:subcellularLocation |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:UniProtID |
gptkb:P24522
|
| gptkbp:bfsParent |
gptkb:GADD45A
|
| gptkbp:bfsLayer |
7
|