|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:Apo-E
APOE2
APOE3
APOE4
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cardiovascular_disease
|
|
gptkbp:biologicalProcess
|
cholesterol homeostasis
regulation of immune response
lipid metabolic process
|
|
gptkbp:discoveredBy
|
gptkb:Robert_W._Mahley
|
|
gptkbp:discoveredIn
|
1973
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000130203
|
|
gptkbp:expressedIn
|
brain
liver
macrophages
|
|
gptkbp:function
|
cholesterol metabolism
lipid transport
lipid binding
cholesterol transporter activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasPolymorphism
|
gptkb:rs429358
gptkb:rs7412
|
|
gptkbp:HGNC_ID
|
HGNC:613
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GeneID 567
|
|
gptkbp:length
|
359 amino acids
|
|
gptkbp:locatedOnChromosome
|
19
|
|
gptkbp:location
|
extracellular region
extracellular space
plasma lipoprotein particle
|
|
gptkbp:mapType
|
19q13.32
|
|
gptkbp:molecularWeight
|
36 kDa
|
|
gptkbp:officialFullName
|
gptkb:apolipoprotein_E
|
|
gptkbp:OMIM
|
107741
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Apoe
|
|
gptkbp:pathway
|
gptkb:Alzheimer's_disease_pathway
lipoprotein metabolism
reverse cholesterol transport
|
|
gptkbp:product
|
gptkb:apolipoprotein_E
|
|
gptkbp:RefSeq
|
NM_000041
|
|
gptkbp:symbol
|
gptkb:APOE
|
|
gptkbp:UniProtID
|
P02649
|
|
gptkbp:bfsParent
|
gptkb:P0CG47
|
|
gptkbp:bfsLayer
|
7
|