Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
superfamily
|
| gptkbp:activityRegulatedBy |
gptkb:GDIs_(guanine_nucleotide_dissociation_inhibitors)
gptkb:GAPs_(GTPase-activating_proteins) gptkb:GEFs_(guanine_nucleotide_exchange_factors) |
| gptkbp:composedOf |
gptkb:GTPase_proteins
|
| gptkbp:domain |
gptkb:GTP-binding_domain
|
| gptkbp:EC_number |
3.6.5.-
|
| gptkbp:foundIn |
prokaryotes
eukaryotes |
| gptkbp:function |
molecular switch
hydrolyze GTP |
| https://www.w3.org/2000/01/rdf-schema#label |
GTPase superfamily
|
| gptkbp:includes |
gptkb:Arf_family
gptkb:Rab_family gptkb:Ran_family gptkb:Rho_family gptkb:Ras_family gptkb:Dynamin_family |
| gptkbp:mutationAssociatedWith |
gptkb:cancer
developmental disorders neurological disorders |
| gptkbp:regulates |
cell differentiation
cell proliferation vesicle trafficking cell growth cell migration cell signaling cytoskeleton organization nuclear transport |
| gptkbp:bfsParent |
gptkb:RAS_superfamily
|
| gptkbp:bfsLayer |
5
|