|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
|
|
gptkbp:associatedWith
|
cancer (when mutated)
|
|
gptkbp:component
|
gptkb:plasma_membrane
|
|
gptkbp:encodedBy
|
Hras gene
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:family
|
gptkb:Ras_family
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
|
|
gptkbp:function
|
GTP binding
GTPase activity
|
|
gptkbp:gene
|
Hras
|
|
gptkbp:GOProcess
|
regulation of cell proliferation
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GTPase HRas (mouse)
|
|
gptkbp:involvedIn
|
signal transduction
MAPK cascade
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7
|
|
gptkbp:location
|
gptkb:plasma_membrane
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:mutationAssociatedWith
|
oncogenic transformation
|
|
gptkbp:orthologIn
|
gptkb:HRAS_(human)
Hras1 (rat)
|
|
gptkbp:PDB
|
4Q21
|
|
gptkbp:postTranslationalModification
|
farnesylation
palmitoylation
|
|
gptkbp:regulates
|
activated by GEFs
inactivated by GAPs
|
|
gptkbp:relatedHumanProtein
|
gptkb:HRAS_(human)
|
|
gptkbp:sequence
|
189 amino acids
|
|
gptkbp:structure
|
gptkb:G-domain
|
|
gptkbp:UniProtID
|
gptkb:P01112
|
|
gptkbp:bfsParent
|
gptkb:HRAS_(mouse)
|
|
gptkbp:bfsLayer
|
7
|