GSK (Glycogen synthase kinase)

GPTKB entity

Statements (22)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:associatedWith gptkb:Alzheimer's_disease
gptkb:diabetes
bipolar disorder
gptkbp:biologicalProcess protein phosphorylation
gptkbp:discoveredIn 1980s
gptkbp:encodedBy gptkb:GSK3A_gene
gptkb:GSK3B_gene
gptkbp:form unphosphorylated
gptkbp:foundIn eukaryotes
gptkbp:function phosphorylation of glycogen synthase
gptkbp:hasIsoform gptkb:GSK-3_alpha
gptkb:GSK-3_beta
https://www.w3.org/2000/01/rdf-schema#label GSK (Glycogen synthase kinase)
gptkbp:inhibitedBy lithium
ATP-competitive inhibitors
gptkbp:involvedIn gptkb:Wnt_signaling_pathway
insulin signaling pathway
gptkbp:memberOf serine/threonine protein kinases
gptkbp:regulates glycogen metabolism
gptkbp:bfsParent gptkb:CMGC
gptkbp:bfsLayer 7