|
gptkbp:instanceOf
|
gptkb:protein
gptkb:solute_carrier_family
ABC transporter
|
|
gptkbp:alternativeName
|
gptkb:Glucose_transporter_type_1
gptkb:SLC2A1
|
|
gptkbp:clinicalTrialPhase
|
CSF/blood glucose ratio
|
|
gptkbp:disorderAssociated
|
gptkb:De_Vivo_disease
gptkb:GLUT1_deficiency_syndrome
epilepsy
developmental delay
|
|
gptkbp:encodedBy
|
gptkb:SLC2A1_gene
|
|
gptkbp:foundIn
|
gptkb:kidney
gptkb:placenta
gptkb:blood-brain_barrier
eye
colon
neurons
endothelial cells
astrocytes
erythrocytes
|
|
gptkbp:function
|
facilitated diffusion of glucose
transports dehydroascorbic acid
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GLUT1 transporter
|
|
gptkbp:inhibitedBy
|
gptkb:cytochalasin_B
gptkb:phloretin
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1p34.2
|
|
gptkbp:molecularWeight
|
55 kDa
|
|
gptkbp:mutationAssociatedWith
|
neurological symptoms
reduced glucose transport
|
|
gptkbp:OMIM
|
138140
|
|
gptkbp:orthologIn
|
gptkb:GLUT4
gptkb:GLUT2
gptkb:GLUT3
|
|
gptkbp:PDB
|
4PYP
|
|
gptkbp:regulates
|
gptkb:insulin
gptkb:hypoxia
glucose levels
|
|
gptkbp:relatedTo
|
gptkb:PET_scan_with_FDG
cancer metabolism
tumor imaging
|
|
gptkbp:species
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkb:Rattus_norvegicus
|
|
gptkbp:structure
|
12 transmembrane domains
|
|
gptkbp:substrate
|
gptkb:dehydroascorbic_acid
glucose
|
|
gptkbp:UniProtID
|
P11166
|
|
gptkbp:bfsParent
|
gptkb:dehydroascorbic_acid
|
|
gptkbp:bfsLayer
|
6
|