|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:GLI
glioma-associated oncogene homolog 1
GLI-Kruppel family member 1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:medulloblastoma
gptkb:glioblastoma
basal cell carcinoma
|
|
gptkbp:discoveredBy
|
gptkb:Yusuke_Nakamura
|
|
gptkbp:discoveredIn
|
1987
|
|
gptkbp:encodes
|
GLI1 protein
|
|
gptkbp:Entrez_Gene_ID
|
2735
ENSG00000111087
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:HGNC_ID
|
HGNC:4317
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GLI1 gene
|
|
gptkbp:involvedIn
|
gptkb:Hedgehog_signaling_pathway
|
|
gptkbp:locatedOnChromosome
|
12q13.3
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
|
|
gptkbp:OMIM
|
165220
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Gli1
|
|
gptkbp:proteinFamily
|
GLI family of zinc finger proteins
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell proliferation
|
|
gptkbp:transcriptionRegulatorOf
|
target genes in Hedgehog pathway
|
|
gptkbp:UniProtID
|
P08151
|
|
gptkbp:bfsParent
|
gptkb:GLI
|
|
gptkbp:bfsLayer
|
7
|