Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:ARF_family_GTPases
|
| gptkbp:catalyzes |
GDP-GTP exchange on ARF proteins
|
| gptkbp:conservedIn |
eukaryotes
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:foundIn |
ARF guanine nucleotide exchange factors
|
| gptkbp:function |
guanine nucleotide exchange factor activity
|
| https://www.w3.org/2000/01/rdf-schema#label |
Sec7 domain
|
| gptkbp:InterPro |
IPR000397
|
| gptkbp:mutationAssociatedWith |
defects in membrane trafficking
|
| gptkbp:namedAfter |
Sec7 protein in yeast
|
| gptkbp:presentIn |
gptkb:EFA6
gptkb:BIG1 gptkb:GBF1 BIG2 BRAG proteins cytohesins yeast Sec7 protein |
| gptkbp:proteinFamily |
PF12783
|
| gptkbp:requires |
vesicle trafficking
|
| gptkbp:structure |
alpha-helical
|
| gptkbp:bfsParent |
gptkb:GEF
gptkb:Guanine_nucleotide_exchange_factors_(GEFs) |
| gptkbp:bfsLayer |
6
|