GTPase-activating protein (GAP)
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:GAP
|
| gptkbp:example |
gptkb:ArfGAP
gptkb:RasGAP gptkb:RhoGAP |
| gptkbp:foundIn |
eukaryotic cells
prokaryotic cells |
| gptkbp:function |
stimulate GTPase activity
|
| https://www.w3.org/2000/01/rdf-schema#label |
GTPase-activating protein (GAP)
|
| gptkbp:involvedIn |
signal transduction
cell signaling |
| gptkbp:mechanismOfAction |
increase hydrolysis of GTP to GDP
|
| gptkbp:opposedBy |
guanine nucleotide exchange factor (GEF)
|
| gptkbp:regulates |
gptkb:Ras_proteins
Arf proteins GTP-binding proteins Rab proteins Ran proteins Rho proteins small G proteins |
| gptkbp:role |
turning off GTPase signaling
|
| gptkbp:bfsParent |
gptkb:GEF
|
| gptkbp:bfsLayer |
6
|