|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
AXLLG
GAS-6
growth arrest-specific gene 6 protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:systemic_lupus_erythematosus
gptkb:acute_myeloid_leukemia
atherosclerosis
cancer progression
thrombosis
inflammation
COVID-19 severity
|
|
gptkbp:discoveredBy
|
Varnum et al.
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:domain
|
EGF-like domain
Gla domain
SHBG-like domain
|
|
gptkbp:encodes
|
growth arrest-specific protein 6
|
|
gptkbp:Entrez_Gene_ID
|
2621
ENSG00000183087
|
|
gptkbp:expressedIn
|
liver
bone marrow
endothelial cells
vascular smooth muscle cells
|
|
gptkbp:fullName
|
growth arrest-specific 6
|
|
gptkbp:function
|
cell proliferation regulation
cell survival regulation
inhibits apoptosis
cell migration regulation
ligand for receptor tyrosine kinases
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:4168
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GAS6
|
|
gptkbp:interactsWith
|
gptkb:AXL
MERTK
TYRO3
|
|
gptkbp:length
|
678 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:13q34
|
|
gptkbp:molecularWeight
|
75 kDa
|
|
gptkbp:OMIM
|
600441
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Gas6
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
TAM receptor signaling pathway
|
|
gptkbp:postTranslationalModification
|
gamma-carboxylation
|
|
gptkbp:proteinFamily
|
vitamin K-dependent proteins
|
|
gptkbp:UniProtID
|
Q14393
|
|
gptkbp:bfsParent
|
gptkb:AXL
|
|
gptkbp:bfsLayer
|
7
|