|
gptkbp:instanceOf
|
gptkb:voltage-gated_potassium_channel
gptkb:protein
|
|
gptkbp:activatedBy
|
gptkb:gamma-aminobutyric_acid
|
|
gptkbp:associatedWith
|
epilepsy
muscle relaxation
insomnia
anxiety disorders
sedation
|
|
gptkbp:discoveredIn
|
1977
|
|
gptkbp:encodedBy
|
gptkb:GABRA1_gene
gptkb:GABRB2_gene
gptkb:GABRG2_gene
|
|
gptkbp:enemyOf
|
gptkb:bicuculline
gptkb:picrotoxin
|
|
gptkbp:foundIn
|
central nervous system
|
|
gptkbp:function
|
mediates inhibitory neurotransmission
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GABAA receptor
|
|
gptkbp:inhibitedBy
|
gptkb:flumazenil
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_15
gptkb:chromosome_X
gptkb:chromosome_5
gptkb:chromosome_4
|
|
gptkbp:MeSH_ID
|
D005754
|
|
gptkbp:modulatedBy
|
gptkb:benzodiazepines
ethanol
barbiturates
general anesthetics
neurosteroids
|
|
gptkbp:OMIM
|
137160
|
|
gptkbp:PDB
|
6HUO
6HUP
|
|
gptkbp:permeableTo
|
chloride ions
|
|
gptkbp:relatedTo
|
gptkb:GABAB_receptor
gptkb:GABAC_receptor
|
|
gptkbp:structure
|
pentameric
|
|
gptkbp:subunit
|
alpha subunit
beta subunit
gamma subunit
delta subunit
epsilon subunit
pi subunit
rho subunit
theta subunit
|
|
gptkbp:target
|
general anesthetics
anticonvulsant drugs
anxiolytic drugs
sedative drugs
hypnotic drugs
muscle relaxant drugs
|
|
gptkbp:UniProtID
|
P14867
|
|
gptkbp:bfsParent
|
gptkb:gabazine
gptkb:SL_706
|
|
gptkbp:bfsLayer
|
7
|