|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:associatedWith
|
addiction
epilepsy
anxiety
spasticity
|
|
gptkbp:discoveredBy
|
Norman Bowery
|
|
gptkbp:discoveredIn
|
1980
|
|
gptkbp:encodedBy
|
gptkb:GABBR1
gptkb:GABBR2
|
|
gptkbp:enemyOf
|
gptkb:CGP_35348
gptkb:baclofen
gptkb:phaclofen
gptkb:saclofen
|
|
gptkbp:form
|
heterodimer
|
|
gptkbp:foundIn
|
central nervous system
peripheral nervous system
|
|
gptkbp:function
|
inhibitory neurotransmission
|
|
gptkbp:GO_term
|
GO:0004890
GO:0007186
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GABAB receptor
|
|
gptkbp:inhibitedBy
|
adenylyl cyclase
|
|
gptkbp:ligand
|
gptkb:gamma-aminobutyric_acid
|
|
gptkbp:locatedOn
|
postsynaptic membrane
presynaptic membrane
|
|
gptkbp:modulatedBy
|
gptkb:potassium_channels
calcium channels
|
|
gptkbp:OMIM
|
603540
|
|
gptkbp:regulates
|
neurotransmitter release
neuronal excitability
|
|
gptkbp:subunit
|
GABAB1
GABAB2
|
|
gptkbp:target
|
antispastic drugs
muscle relaxants
|
|
gptkbp:type
|
G protein-coupled pathway
|
|
gptkbp:UniProtID
|
gptkb:O75899
gptkb:Q9UBS5
|
|
gptkbp:bfsParent
|
gptkb:CGP_35348
gptkb:O75899_(GABBR2)
gptkb:phaclofen
|
|
gptkbp:bfsLayer
|
7
|