Statements (22)
Predicate | Object |
---|---|
gptkbp:instanceOf |
cell cycle checkpoint
|
gptkbp:alsoKnownAs |
gptkb:restriction_point
|
gptkbp:dysfunction_can_lead_to |
gptkb:cancer
|
gptkbp:guarantees |
cell is ready for DNA synthesis
|
https://www.w3.org/2000/01/rdf-schema#label |
G1 checkpoint
|
gptkbp:involves |
gptkb:cyclin_D
gptkb:retinoblastoma_protein_(Rb) gptkb:p53_protein gptkb:cyclin-dependent_kinases |
gptkbp:location |
late G1 phase
|
gptkbp:monitors |
DNA damage
nutrient availability cell size |
gptkbp:partOf |
cell cycle
|
gptkbp:precededBy |
gptkb:S_phase
|
gptkbp:regulates |
cell cycle progression
|
gptkbp:response |
growth factors
antigrowth signals |
gptkbp:triggeredBy |
apoptosis
cell cycle arrest |
gptkbp:bfsParent |
gptkb:G1
|
gptkbp:bfsLayer |
6
|