Statements (17)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cell cycle checkpoint
|
| gptkbp:alsoKnownAs |
R point
|
| gptkbp:discoveredBy |
gptkb:Arthur_Pardee
|
| gptkbp:discoveredIn |
1974
|
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
|
| gptkbp:function |
controls cell cycle progression
determines commitment to cell division |
| https://www.w3.org/2000/01/rdf-schema#label |
restriction point
|
| gptkbp:importantFor |
prevents uncontrolled cell proliferation
|
| gptkbp:irreversibleAfter |
passing the restriction point
|
| gptkbp:locatedIn |
G1 phase
|
| gptkbp:regulates |
gptkb:retinoblastoma_protein
gptkb:cyclin-dependent_kinases growth factors entry into S phase |
| gptkbp:bfsParent |
gptkb:G1
|
| gptkbp:bfsLayer |
6
|