Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
genetic disorder |
| gptkbp:affects |
gptkb:nervous_system
|
| gptkbp:affectsCellType |
motor neurons
|
| gptkbp:associatedWith |
gptkb:C9orf72_gene_mutation
gptkb:FUS_gene_mutation gptkb:SOD1_gene_mutation gptkb:TARDBP_gene_mutation |
| gptkbp:causedBy |
genetic disorder
|
| gptkbp:firstDescribed |
19th century
|
| gptkbp:frequency |
rare
|
| https://www.w3.org/2000/01/rdf-schema#label |
familial ALS
|
| gptkbp:ICD-10_code |
G12.21
|
| gptkbp:inheritance |
autosomal dominant
autosomal recessive |
| gptkbp:onset |
adulthood
|
| gptkbp:prevalence |
5-10% of ALS cases
|
| gptkbp:prognosis |
progressive
fatal |
| gptkbp:riskFactor |
family history of ALS
|
| gptkbp:subclassOf |
amyotrophic lateral sclerosis
|
| gptkbp:symptom |
respiratory failure
difficulty speaking difficulty swallowing muscle atrophy muscle weakness |
| gptkbp:treatment |
gptkb:edaravone
gptkb:riluzole |
| gptkbp:bfsParent |
gptkb:Lou_Gehrig's_disease
gptkb:SOD1 |
| gptkbp:bfsLayer |
5
|