Furin (gene)

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias gptkb:PACE
gptkb:PCSK3
gptkbp:associatedWith gptkb:Alzheimer's_disease
gptkb:cancer
infectious diseases
cystic fibrosis
gptkbp:discoveredBy 1990
gptkbp:encodes furin protein
gptkbp:Entrez_Gene_ID 5045
ENSG00000140564
gptkbp:expressedIn various tissues
gptkbp:function cleavage of precursor proteins
proprotein convertase
gptkbp:geneType protein-coding
gptkbp:HGNC_ID HGNC:4016
https://www.w3.org/2000/01/rdf-schema#label Furin (gene)
gptkbp:locatedOnChromosome gptkb:chromosome_15
gptkbp:OMIM 136950
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse gptkb:Furin_(mouse_gene)
gptkbp:pathway viral entry into host cell
protein processing in the secretory pathway
gptkbp:proteinFamily proprotein convertase family
subtilisin-like serine endoprotease family
gptkbp:symbol gptkb:FURIN
gptkbp:UniProtID P09958
gptkbp:bfsParent gptkb:FUN
gptkbp:bfsLayer 7