Forkhead box O

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:abbreviation gptkb:FOXO
gptkbp:associatedWith gptkb:cancer
gptkb:diabetes
neurodegenerative diseases
gptkbp:contains gptkb:FOXO1
gptkb:FOXO3
gptkb:FOXO4
gptkb:FOXO6
gptkbp:discoveredBy 1990s
gptkbp:foundIn animals
humans
mammals
gptkbp:function transcription factor
gptkbp:gene gptkb:FOXO
https://www.w3.org/2000/01/rdf-schema#label Forkhead box O
gptkbp:namedAfter forkhead DNA-binding domain
gptkbp:regulates gptkb:PI3K/AKT_pathway
apoptosis
longevity
DNA repair
metabolism
phosphorylation
immune response
cell cycle
oxidative stress response
insulin signaling pathway
gptkbp:relatedTo aging
gptkbp:subclassOf forkhead box proteins
gptkbp:bfsParent gptkb:FOXO
gptkbp:bfsLayer 7