Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Cell
|
| gptkbp:activatedBy |
Myofibroblast
|
| gptkbp:canBe |
Morphology
Immunohistochemistry |
| gptkbp:canBeCulturedIn |
In vitro
|
| gptkbp:canDifferentiateInto |
Myofibroblast
|
| gptkbp:derivedFrom |
Mesenchymal stem cell
|
| gptkbp:firstDescribed |
gptkb:Rudolf_Virchow
|
| gptkbp:foundIn |
Connective tissue
|
| gptkbp:function |
Wound healing
Produce collagen Synthesize extracellular matrix |
| gptkbp:hasNucleus |
Oval nucleus
|
| https://www.w3.org/2000/01/rdf-schema#label |
Fibroblast
|
| gptkbp:marking |
Vimentin
FSP1 Fibroblast-specific protein 1 PDGFR-α |
| gptkbp:presentIn |
gptkb:Heart
gptkb:skin gptkb:Blood_vessels Lungs Liver Kidney Organs Cornea Ligaments Tendons Gingiva |
| gptkbp:produces |
gptkb:Glycosaminoglycans
Proteoglycans Fibronectin Collagen type I Collagen type III Elastin |
| gptkbp:response |
gptkb:IL-1
gptkb:TNF-alpha gptkb:FGF gptkb:PDGF gptkb:TGF-beta Cytokines Growth factors Mechanical stress |
| gptkbp:role |
gptkb:Scleroderma
Cancer stroma Fibrosis Keloid formation |
| gptkbp:roleInAging |
Reduced collagen production
|
| gptkbp:shape |
Spindle-shaped
|
| gptkbp:bfsParent |
gptkb:IDUA_HUMAN
gptkb:Connective_Tissue |
| gptkbp:bfsLayer |
7
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