Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
polysaccharide
|
| gptkbp:alsoKnownAs |
GAGs
|
| gptkbp:biosynthesized_from |
glycosyltransferases
|
| gptkbp:charge |
highly negatively charged
|
| gptkbp:component |
extracellular matrix
|
| gptkbp:composedOf |
repeating disaccharide units
|
| gptkbp:degradedBy |
glycosidases
|
| gptkbp:excludes |
branched chains
|
| gptkbp:firstDescribed |
early 20th century
|
| gptkbp:foundIn |
gptkb:skeletal_muscle
|
| gptkbp:function |
provide structural support
bind water mediate cell adhesion regulate cell signaling |
| https://www.w3.org/2000/01/rdf-schema#label |
Glycosaminoglycans
|
| gptkbp:importantFor |
development
wound healing cell migration joint lubrication tissue hydration |
| gptkbp:interactsWith |
gptkb:integrins
gptkb:fibronectin cytokines growth factors collagen proteoglycans |
| gptkbp:location |
gptkb:skin
lungs collagen cornea heart valves blood vessels tendons synovial fluid |
| gptkbp:monomer |
uronic acid
amino sugar |
| gptkbp:role |
osteoarthritis
inflammation mucopolysaccharidoses |
| gptkbp:solubility |
water soluble
|
| gptkbp:type |
gptkb:heparin
dermatan sulfate heparan sulfate hyaluronic acid chondroitin sulfate keratan sulfate |
| gptkbp:usedIn |
biomedical research
tissue engineering |
| gptkbp:bfsParent |
gptkb:N-acetylglucosamine
|
| gptkbp:bfsLayer |
6
|