|
gptkbp:instanceOf
|
gptkb:autoimmune_disease
gptkb:connective_tissue_disease
|
|
gptkbp:affects
|
gptkb:skin
adults
children
internal organs
|
|
gptkbp:cause
|
gptkb:unknown
|
|
gptkbp:complication
|
heart failure
kidney failure
pulmonary hypertension
malabsorption
|
|
gptkbp:diagnosedBy
|
clinical examination
skin biopsy
autoantibody tests
|
|
gptkbp:firstDescribed
|
1753
|
|
gptkbp:ICD-10_code
|
M34
|
|
gptkbp:MeSH_ID
|
D012595
|
|
gptkbp:namedFor
|
gptkb:Carlo_Curzio
|
|
gptkbp:OMIM
|
181750
|
|
gptkbp:prevalence
|
rare
|
|
gptkbp:riskFactor
|
family history
female sex
exposure to silica dust
|
|
gptkbp:subspecies
|
gptkb:systemic_sclerosis
gptkb:diffuse_cutaneous_scleroderma
gptkb:limited_cutaneous_scleroderma
gptkb:localized_scleroderma
|
|
gptkbp:symptom
|
gptkb:Raynaud's_phenomenon
fatigue
joint pain
telangiectasia
weight loss
difficulty swallowing
muscle weakness
shortness of breath
pulmonary fibrosis
calcinosis
esophageal dysfunction
skin thickening
digital ulcers
renal crisis
|
|
gptkbp:treatment
|
gptkb:proton_pump_inhibitors
physical therapy
ACE inhibitors
immunosuppressive drugs
vasodilators
|
|
gptkbp:bfsParent
|
gptkb:Boletales
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Scleroderma
|