Scleroderma

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf autoimmune disease
connective tissue disease
gptkbp:affects gptkb:skin
adults
children
internal organs
gptkbp:cause unknown
gptkbp:complication heart failure
kidney failure
pulmonary hypertension
malabsorption
gptkbp:diagnosedBy clinical examination
skin biopsy
autoantibody tests
gptkbp:firstDescribed 1753
https://www.w3.org/2000/01/rdf-schema#label Scleroderma
gptkbp:ICD-10_code M34
gptkbp:MeSH_ID D012595
gptkbp:namedFor gptkb:Carlo_Curzio
gptkbp:OMIM 181750
gptkbp:prevalence rare
gptkbp:riskFactor family history
female sex
exposure to silica dust
gptkbp:subspecies gptkb:systemic_sclerosis
gptkb:diffuse_cutaneous_scleroderma
gptkb:limited_cutaneous_scleroderma
gptkb:localized_scleroderma
gptkbp:symptom gptkb:Raynaud's_phenomenon
fatigue
joint pain
telangiectasia
weight loss
difficulty swallowing
muscle weakness
shortness of breath
pulmonary fibrosis
calcinosis
esophageal dysfunction
skin thickening
digital ulcers
renal crisis
gptkbp:treatment gptkb:proton_pump_inhibitors
physical therapy
ACE inhibitors
immunosuppressive drugs
vasodilators
gptkbp:bfsParent gptkb:Boletales
gptkbp:bfsLayer 6