Fas-Associated Death Domain protein
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:FADD
|
| gptkbp:alternativeName |
gptkb:MORT1
FADD/MORT1 |
| gptkbp:discoveredIn |
1995
|
| gptkbp:domain |
gptkb:death_effector_domain
death domain |
| gptkbp:encodedBy |
gptkb:FADD_gene
|
| gptkbp:Entrez_Gene_ID |
8772
|
| gptkbp:function |
apoptosis signaling
death receptor signaling |
| https://www.w3.org/2000/01/rdf-schema#label |
Fas-Associated Death Domain protein
|
| gptkbp:interactsWith |
gptkb:Fas_receptor
gptkb:TRADD gptkb:Caspase-10 gptkb:Caspase-8 |
| gptkbp:involvedIn |
extrinsic apoptotic pathway
death-inducing signaling complex (DISC) formation |
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:locatedOnChromosome |
gptkb:11q13.3
|
| gptkbp:molecularWeight |
23 kDa
|
| gptkbp:orthologIn |
gptkb:mouse
gptkb:zebrafish right |
| gptkbp:phosphorylates |
Ser194
|
| gptkbp:role |
inflammation
immune response cell death |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:UniProtID |
gptkb:Q13158
|
| gptkbp:bfsParent |
gptkb:FADD
|
| gptkbp:bfsLayer |
7
|