Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alias |
AP-1 transcription factor subunit FOSL2
FOS-related antigen 2 FRA2 |
| gptkbp:associatedWith |
gptkb:cancer
fibrosis metabolic disorders |
| gptkbp:encodes |
FOSL2 protein
|
| gptkbp:Entrez_Gene_ID |
2355
ENSG00000125740 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:fullName |
FOS like 2, AP-1 transcription factor subunit
|
| gptkbp:function |
transcription factor
|
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
HGNC:3801
|
| https://www.w3.org/2000/01/rdf-schema#label |
FOSL2
|
| gptkbp:interactsWith |
gptkb:JUN
gptkb:FOSB gptkb:FOS gptkb:JUNB ATF proteins JUND |
| gptkbp:involvedIn |
apoptosis
cell proliferation differentiation immune response tumorigenesis adipogenesis osteoclast differentiation |
| gptkbp:locatedOnChromosome |
2
2p22-p23 |
| gptkbp:memberOf |
AP-1 transcription factor complex
|
| gptkbp:molecularWeight |
35 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Fosl2
|
| gptkbp:postTranslationalModification |
phosphorylation
ubiquitination |
| gptkbp:regulates |
gptkb:Wnt_signaling
gene expression cell migration cell cycle inflammatory response osteoblast differentiation TGF-beta signaling extracellular matrix production MAPK signaling NF-kB signaling |
| gptkbp:subcellularLocation |
gptkb:nucleus
|
| gptkbp:transcriptionRegulator |
yes
|
| gptkbp:UniProtID |
P15408
|
| gptkbp:bfsParent |
gptkb:FOSL
|
| gptkbp:bfsLayer |
6
|