|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
AP-1 transcription factor subunit FOSL2
FOS-related antigen 2
FRA2
|
|
gptkbp:associatedWith
|
gptkb:cancer
fibrosis
metabolic disorders
|
|
gptkbp:encodes
|
FOSL2 protein
|
|
gptkbp:Entrez_Gene_ID
|
2355
ENSG00000125740
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
FOS like 2, AP-1 transcription factor subunit
|
|
gptkbp:function
|
gptkb:transcription_factor
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:3801
|
|
gptkbp:interactsWith
|
gptkb:JUN
gptkb:FOSB
gptkb:FOS
gptkb:JUNB
ATF proteins
JUND
|
|
gptkbp:involvedIn
|
gptkb:immune_response
apoptosis
cell proliferation
differentiation
tumorigenesis
adipogenesis
osteoclast differentiation
|
|
gptkbp:locatedOnChromosome
|
2
2p22-p23
|
|
gptkbp:memberOf
|
AP-1 transcription factor complex
|
|
gptkbp:molecularWeight
|
35 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Fosl2
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:regulates
|
gptkb:Wnt_signaling
gene expression
cell migration
cell cycle
inflammatory response
osteoblast differentiation
TGF-beta signaling
extracellular matrix production
MAPK signaling
NF-kB signaling
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:transcriptionRegulator
|
yes
|
|
gptkbp:UniProtID
|
P15408
|
|
gptkbp:bfsParent
|
gptkb:Fos_protein_family
gptkb:Fra-2
gptkb:FOSL
gptkb:Fos_family_proteins
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FOSL2
|