|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:2-phospho-D-glycerate_hydro-lyase
gptkb:ENO1
gptkb:phosphopyruvate_hydratase
MPB-1
|
|
gptkbp:alternativeTo
|
plasminogen receptor
|
|
gptkbp:antigen_for
|
autoantibodies in Hashimoto's encephalopathy
autoantibodies in cancer-associated retinopathy
|
|
gptkbp:associatedWith
|
gptkb:cancer
autoimmune diseases
|
|
gptkbp:catalyzes
|
conversion of 2-phosphoglycerate to phosphoenolpyruvate
|
|
gptkbp:cofactor
|
Mg2+
Mn2+
|
|
gptkbp:discoveredBy
|
1934
|
|
gptkbp:EC_number
|
4.2.1.11
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
gptkb:kidney
brain
liver
erythrocytes
most tissues
|
|
gptkbp:form
|
dimer
|
|
gptkbp:foundIn
|
gptkb:cell_membrane
gptkb:cytoplasm
|
|
gptkbp:gene
|
gptkb:ENO1
|
|
gptkbp:has_moonlighting_function
|
cell surface receptor for plasminogen
transcriptional repressor (MBP-1)
|
|
gptkbp:hasIsoform
|
gptkb:beta-enolase
neuron-specific enolase (gamma-enolase)
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
alpha-enolase
|
|
gptkbp:inhibitedBy
|
gptkb:fluoride
phosphonoacetohydroxamate
|
|
gptkbp:involves
|
energy metabolism
glycolysis
|
|
gptkbp:locatedOnChromosome
|
gptkb:1p36.23
|
|
gptkbp:molecularWeight
|
47 kDa
|
|
gptkbp:OMIM
|
172430
|
|
gptkbp:participatedIn
|
gluconeogenesis
|
|
gptkbp:PDB
|
3B97
|
|
gptkbp:product
|
phosphoenolpyruvate
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:2-phosphoglycerate
|
|
gptkbp:target
|
autoantibodies
|
|
gptkbp:UniProtID
|
gptkb:P06733
|
|
gptkbp:used_in
|
diagnosis of autoimmune diseases
diagnosis of some cancers
|
|
gptkbp:usedFor
|
biomarker
|
|
gptkbp:bfsParent
|
gptkb:Enolase
|
|
gptkbp:bfsLayer
|
7
|