Early Growth Response Protein 1

URI: https://gptkb.org/entity/Early_Growth_Response_Protein_1
GPTKB entity
Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:Krox-24
gptkb:NGFI-A
gptkb:TIS8
gptkb:Zif268
gptkbp:associatedWith gptkb:cancer
wound healing
neural plasticity
gptkbp:biologicalProcess DNA binding
gptkbp:cellularComponent gptkb:nucleus
gptkbp:contains three C2H2-type zinc fingers
gptkbp:encodedBy gptkb:EGR1_gene
gptkbp:Entrez_Gene_ID gptkb:ENSG00000120738
gptkbp:function regulation of apoptosis
transcription factor
regulation of cell growth
regulation of differentiation
gptkbp:gene gptkb:EGR1
gptkbp:HGNC_ID 3238
https://www.w3.org/2000/01/rdf-schema#label Early Growth Response Protein 1
gptkbp:inducedBy gptkb:trauma
stress
growth factors
gptkbp:length 543
gptkbp:locatedOnChromosome 5q31.2
gptkbp:molecularWeight 57 kDa
gptkbp:OMIM 128990
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse gptkb:Egr1
gptkbp:postTranslationalModification phosphorylation
sumoylation
acetylation
gptkbp:RefSeq NP_001954.2
gptkbp:regulates gptkb:synaptic_plasticity
apoptosis
cell proliferation
angiogenesis
cell migration
immune response
cell cycle
neuronal activity
learning and memory
inflammatory response
fibrosis
vascular remodeling
expression of target genes
gptkbp:UniProtID gptkb:P18146
gptkbp:bfsParent gptkb:EGA_(gene)
gptkbp:bfsLayer 6