Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:ACE
gptkb:angiotensin-converting_enzyme |
| gptkbp:associatedWith |
heart failure
hypertension diabetic nephropathy |
| gptkbp:biologicalProcess |
regulation of blood pressure
peptidyl-dipeptidase activity |
| gptkbp:catalyzes |
conversion of angiotensin I to angiotensin II
release of a C-terminal dipeptide from an oligopeptide substrate inactivation of bradykinin |
| gptkbp:cofactor |
zinc
|
| gptkbp:enzymeCommissionNumber |
3.4.15.1
|
| gptkbp:foundIn |
mammals
endothelial cells lung tissue |
| gptkbp:gene |
gptkb:ACE
|
| https://www.w3.org/2000/01/rdf-schema#label |
EC 3.4.15.1
|
| gptkbp:inhibitedBy |
gptkb:enalapril
gptkb:captopril gptkb:lisinopril |
| gptkbp:recommendation |
gptkb:peptidyl-dipeptidase_A
|
| gptkbp:systematicName |
peptidyl-L-amino-acid hydrolase
|
| gptkbp:UniProtID |
P12821
|
| gptkbp:bfsParent |
gptkb:ACE_(gene)
gptkb:peptidase_M2_family |
| gptkbp:bfsLayer |
6
|