|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CD143
gptkb:DCP1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cardiovascular_disease
hypertension
|
|
gptkbp:biologicalProcess
|
gptkb:renin-angiotensin_system
peptidyl-dipeptidase activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
gptkb:Leonard_T._Skeggs
|
|
gptkbp:encodes
|
gptkb:angiotensin-converting_enzyme
|
|
gptkbp:Entrez_Gene_ID
|
1636
|
|
gptkbp:enzymeCommissionNumber
|
gptkb:EC_3.4.15.1
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
gptkb:testis
|
|
gptkbp:function
|
regulation of blood pressure
conversion of angiotensin I to angiotensin II
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasPolymorphism
|
insertion/deletion (I/D) polymorphism
|
|
gptkbp:HGNC_ID
|
2707
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ACE (gene)
|
|
gptkbp:length
|
26 exons
|
|
gptkbp:locatedOnChromosome
|
gptkb:17q23.3
gptkb:chromosome_17
|
|
gptkbp:OMIM
|
106180
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Ace
|
|
gptkbp:product
|
gptkb:angiotensin-converting_enzyme
|
|
gptkbp:significance
|
pharmacogenomics of ACE inhibitors
|
|
gptkbp:symbol
|
gptkb:ACE
|
|
gptkbp:UniProtID
|
P12821
|
|
gptkbp:bfsParent
|
gptkb:ACE
|
|
gptkbp:bfsLayer
|
5
|