Dual specificity protein phosphatase 4
GPTKB entity
Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:MKP-2
Mitogen-activated protein kinase phosphatase 2 |
| gptkbp:associatedWith |
cancer (various types)
|
| gptkbp:biologicalProcess |
protein tyrosine phosphatase activity
protein serine/threonine phosphatase activity |
| gptkbp:Entrez_Gene_ID |
1846
|
| gptkbp:enzymeClassification |
gptkb:EC_3.1.3.16
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
regulates apoptosis
regulates cellular proliferation regulates differentiation dephosphorylates MAP kinases |
| gptkbp:gene |
gptkb:DUSP4
|
| gptkbp:HGNC_ID |
3070
|
| https://www.w3.org/2000/01/rdf-schema#label |
Dual specificity protein phosphatase 4
|
| gptkbp:locatedOnChromosome |
gptkb:8p12
|
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:OMIM |
601135
|
| gptkbp:regulates |
gptkb:ERK1/2
gptkb:JNK gptkb:p38_MAPK gptkb:MAPK_signaling_pathway |
| gptkbp:substrate |
phosphotyrosine
phosphoserine phosphothreonine |
| gptkbp:UniProtID |
gptkb:Q13115
|
| gptkbp:bfsParent |
gptkb:DUSP4
|
| gptkbp:bfsLayer |
7
|