DNA mismatch repair protein Msh6
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:MutS_homolog_6
|
| gptkbp:associatedWith |
gptkb:hereditary_nonpolyposis_colorectal_cancer
|
| gptkbp:biologicalProcess |
DNA repair
cell cycle regulation |
| gptkbp:encodedBy |
MSH6 gene
|
| gptkbp:firstDescribed |
1995
|
| gptkbp:formsComplexWith |
gptkb:MSH2_protein
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
DNA mismatch repair
|
| gptkbp:GO_term |
GO:0004300
|
| https://www.w3.org/2000/01/rdf-schema#label |
DNA mismatch repair protein Msh6
|
| gptkbp:interactsWith |
gptkb:MLH1
gptkb:PMS2 gptkb:PCNA |
| gptkbp:locatedOnChromosome |
2p16.3
|
| gptkbp:molecularWeight |
approximately 150 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
gptkb:Lynch_syndrome gptkb:endometrial_cancer |
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae |
| gptkbp:reviewedBy |
gptkb:UniProtKB/Swiss-Prot
|
| gptkbp:structure |
contains MutS domain
contains PWWP domain |
| gptkbp:subcellularLocation |
gptkb:nucleus
|
| gptkbp:UniProtID |
P52701
|
| gptkbp:bfsParent |
gptkb:MSH6
|
| gptkbp:bfsLayer |
6
|